My doctor recommended that I go and see an Orthopedic Doctor for my worsening knee pain. He prescribed a prescription gel that I was to apply four times a day. Very messy, but I done as he told me for around 2 weeks with no improvement. I went back. They xrayed my knees and told me the joints were worn out. Bone rubbing against bone, with nothing there to cushion the shock. He gave me a shot in each knee. It helped for around a week. I couldn't get any more shots for a month, so I toughed it out. I went back in for more shots. My doctor was gone, I had a new doctor. He gave me the first shot, not too uncomfortable. Time for the second shot, in the worst of my two knees. I have never felt such pain in all my life! Tears were streaming down my cheeks, I had a tight grip of the table I was sitting on. Finally he stopped, pulled the needle out and said "I can't do this to you!" He was so sorry and didn't know what had went wrong. He then sent me for aqua therapy. This helped, while I was moving around in the 96 degree pool. My insurance would not pay for more than 2 months of treatments. It was very expensive to pay out-of-pocket. Plus since I could only go twice a week, my knees hurt just as bad the other 5 days of the week.I went back to see my doctor and he recommended something I had never heard of before. He told me that vets were having amazing success in horses with leg sprains and problems, after they started using this product. I stopped at a pharmacy and bought a bottle of Glucosamine Chondroitin MSM. I buy a lot of vitamins and supplements, most I can never tell if they are working or not. I take 3 capsules per day of these, one in the morning and two at night. I saw results within FOUR DAYS! Then I found these on Facebook. I think they workfaster because they are not a solid pill, like I found locally in the pharmacy. I will never, ever run out of these again!It hurt so bad to walk before, with a constant audible crunching of bone rubbing against bone. Now that is mainly gone. These amazing pills put the cushion back, and I LOVE them!UPDATE: I have taken these for months now. My knee pain is gone! There were a few times that I went for a few days, forgetting to take them. I will not make that mistake again! Now when I fill my weekly prescription box, these are included. To me, they are more important than some of the prescriptions that I am taking!