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Nitric Oxide Bundle - L-Citrulline & Beetroot

Nitric Oxide Bundle - L-Citrulline & Beetroot

£49.98

£39.99

SAVE £9.99

Just £1.33 Per Day

1. Supply

1 Month

2 Months

3 Months

How much in a 1 month supply?

120 Beetroot Tablets

150g Unflavoured L-Citrulline

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SCIENTIFIC STUDIES

We have summarised some of the most interesting scientific studies on beetroot and L-citrulline.

It is important to note that a decrease between 5 and 12 mmHg of systolic blood pressure and between 5 and 6 mmHg of diastolic blood pressure is associated with a 14–38% risk reduction in stroke and a 21% risk reduction of death due to coronary disease.

Study 1

Study type:

Randomised, double-blind, placebo-controlled trial

Dose:

250 mL/day of beetroot juice (containing ~6.4mmol of nitrate) or a placebo (250 mL of nitrate-depleted beetroot juice)

Participants:

64 hypertensive men and women aged 18 to 85

Duration:

4 weeks

Results:

Daily supplementation with beetroot juice (dietary nitrate) was associated with a reduction in blood pressure. Specifically, the mean 24h ambulatory blood pressure decreased by 7.7/5.2 mmHg and the mean clinical blood pressure decreased by 7.7/2.4 mmHg. These reductions are clinically significant as they resemble the average reduction in blood pressure after a single anti-hypertensive drug at standard dose (9.1/5.5 mmHg). The authors of the study suggested that dietary nitrate could be used as an adjunctive therapy for managing hypertension.

Year:

2014

Link:

https://doi.org/10.1161/HYPERTENSIONAHA.114.04675

Study 2

Study type:

Randomised, double-blind, placebo-controlled feasibility trial

Dose

Participants were randomly assigned to consume either:

1. High-nitrate beetroot juice (∼400 mg nitrate) and folic acid (∼5 mg folic acid) (N+F)

2. High-nitrate beetroot juice and placebo (N+P)

3. Nitrate-depleted beetroot juice and placebo (P+P)

Participants:

47 men and women aged 50 to 70 with BMIs between 26 and 29

Duration:

60 days

Results:

Supplementation with beetroot juice (dietary inorganic nitrate) was associated with lower systolic and diastolic blood pressure. At the end of the study, 24h systolic blood pressure dropped by −10.8, −6.1 and −0.3 mmHg in the N+P, N+F, and P+P groups, respectively. There was a significant decrease in 24h diastolic blood pressure in the N+P group (−5.4 mmHg), whereas changes were not significant in the N+F (−1.8 mmHg) and P+P (1.6 mmHg) groups.

Year:

2020

Link:

https://doi.org/10.1093/jn/nxaa170

Study 1

Study type:

Randomised controlled trial

Participants:

12 young adults with normal blood pressure

Dose:

3g of citrulline tablets per day

Duration:

1 week

Results:

Citrulline consumption was associated with a 6% reduction in systolic blood pressure and a 14% reduction in diastolic blood pressure.

Year:

2016

Link:

https://doi.org/10.1007/s00421-016-3418-7

Study 2

Study type:

Randomised controlled trial

Participants:

41 obese postmenopausal women

Duration:

8 weeks

Results:

L-citrulline supplementation was associated with significant reductions in blood pressure.

Year:

2015

Link:

https://doi.org/10.1139/apnm-2015-0465

Study 3

Study type:

Randomised controlled trial

Dose:

3g per day

Participants:

Heart failure patients

Duration:

2 months

Results:

L-citrulline supplementation was associated with significant reductions in systolic and diastolic arterial blood pressure.

Year:

2015

Link:

https://doi.org/10.1139/apnm-2015-0465

Study 4

Study type:

Systematic review

Intervention under study:

Oral supplementation with L-citrulline

Studies reviewed:

8 randomised controlled trials

Results:

The results suggest that L-citrulline supplementation may reduce systolic blood pressure (-4 mmHg). A significant reduction in diastolic blood pressure was observed only in the studies that used doses greater than 6 g of L-citrulline per day.

Year:

2019

Link:

https://pubmed.ncbi.nlm.nih.gov/30788274/

Study 5

Study type:

Randomised controlled trial

Dose:

6 g L-citrulline-malate 2 h prior exercise

Participants:

17 male pre-professional cyclists

Duration:

Acute (before and after a 137-km cycling race)

Results:

After the cycling race, growth hormone levels were higher among participants taking L-citrulline malate than among participants in the control group. L-citrulline supplementation was also associated with higher levels of arginine-derived metabolites such as nitrite, creatinine, ornithine and urea.

Year:

2010

Link:

https://doi.org/10.1007/s00421-010-1509-4

Study 6

Study type:

Randomised placebo-controlled crossover trial

Dose:

2.4g of L-citrulline for 7 days and 2.4 g of L-citrulline 1h before a 4-km cycling time trial on day 8.

Participants:

22 athletically-trained males

Duration:

8 days

Results:

Compared to the placebo, L-citrulline supplementation was associated with a 1.5% reduction in the time taken to complete a 4-km cycling time trial. It was also associated with significant increases in plasma L-arginine levels.

Year:

2016

Link:

https://doi.org/10.1186/s12970-016-0117-z

Study 7

Study type:

Systematic review

Intervention under study:

L-citrulline supplementation before exercise

Studies reviewed:

13 studies comprising 206 participants

Results:

The results show a correlation between citrulline supplements and significant reductions in the rate of perceived exhaustion during physical activity and muscle soreness 24h and 48h after exercise.

The results suggest that athletes may benefit from ingesting either L-citrulline alone or 1h before exercise to resist fatigue or relieve muscle soreness.

Year:

2021

Link:

https://doi.org/10.1016/j.jshs.2020.02.003

Study 1

Study type:

Randomised double-blind placebo-controlled trial

Dose:

There were 4 dosage groups:

1. 3 g/kg/day of citrulline plus 3 mg/kg/day of nitrates

2. 3 g/kg/day of only citrulline

3. 3 mg/kg/day of only nitrate

4. Placebo

Participants:

32 male amateur triathletes with more than 5 years of experience

Duration:

9 weeks

Results:

The study found that 3 g/day of citrulline and 2.1 g/day of beetroot (300 mg/day of dietary nitrate) for 9 weeks was correlated with increased maximal and endurance strength. When compared to citrulline or beetroot supplementation alone, the combination of both supplements was associated with improved performance in tests related to aerobic power.

Year:

2010

Link:

https://doi.org/10.3390/nu14010040

How to use

DOSAGE

Take 5 grams of l-citrulline daily, dissolved in water and stir well. Take one to three beetroot tablets daily, ideally in the morning.
WITH OR WITHOUT FOOD

This bundle can be taken with food or on an empty stomach. However, the impact of food on supplement absorption is often unpredictable as different compounds within food can interact with the supplement in different ways.
On the other hand, taking this bundle with food will slow absorption, which can be beneficial if you want the effects to kick in slower or if you experience nausea when taking the supplement on an empty stomach.

3rd Party Tests

SEE WHAT OUR CUSTOMERS ARE SAYING

Tasty tablets

These tablets taste quite nice for a change. I actually feel as though they are doing me good and have had less cramping in my feet

all good thx

Beetroot Tablets 3000mg - Lower Blood Pressure & Increase Blood Flow

Excellent product

3 week review

The Beetroot capsules are lovely and even though the effects have not been staggeringly significant at the moment I can feel the difference in my pump when I work out and because I am a medium build my veins are popping out a lot more.

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Frequently Asked Questions

Are there any side effects?

Scientific research has shown that L-citrulline is well-tolerated up to 15g/day. In rare cases, amino acids such as L-citrulline may cause gastrointestinal upset. If this occurs, it is important to significantly lower the dosage.

Clinical trials of beetroot supplements have not observed adverse side effects. In rare cases, the red pigment in beetroot called betanin may be excreted in your urine, giving it a slightly red colour. Although harmless, this can be minimised by staying well hydrated.